ATP6V1C1 Antibody

Code CSB-PA002399GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ATP6V1C1
Alternative Names
ATP6C antibody; ATP6D antibody; ATP6V1C1 antibody; ATPase H+ transporting lysosomal (vacuolar proton pump) 42kD antibody; ATPase H+ transporting lysosomal 42kD V1 subunit C isoform 1 antibody; ATPase H+ transporting lysosomal 42kDa V1 subunit C isoform 1 antibody; ATPase H+ transporting lysosomal 42kDa V1 subunit C1 antibody; ATPase H+ transporting lysosomal V1 subunit C1 antibody; FLJ20057 antibody; H(+) transporting two sector ATPase subunit C antibody; H+ ATPase C subunit antibody; H+ transporting ATPase chain C vacuolar antibody; Subunit C of vacuolar proton ATPase V1 domain antibody; V ATPase C subunit antibody; V ATPase subunit C 1 antibody; V-ATPase subunit C 1 antibody; V-type proton ATPase subunit C 1 antibody; Vacuolar ATP synthase subunit C antibody; Vacuolar proton pump 42 kD subunit antibody; Vacuolar proton pump C subunit antibody; Vacuolar proton pump subunit C 1 antibody; Vacuolar protonATPase subunit C VI domain antibody; VATC antibody; VATC1_HUMAN antibody; VATPase C subunit antibody; VATPase subunit C 1 antibody; VMA5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ATP6V1C1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Gene References into Functions
  1. knockdown of C1 reduces breast cancer growth, metastasis, and osteolytic lesion formation. PMID: 28504970
  2. We assessed ATPaseC1 expression in a sample of oral squamous cell carcinoma using tissue microarrays to analyze the relation between ATPaseC1 expression and clinical, histopathological and prognostic parameters. PMID: 25901422
  3. results of our study suggest that high expression of Atp6v1c1 affects the actin structure of cancer cells such that it facilitates breast cancer metastasis PMID: 24454753
  4. Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa. PMID: 21526910
  5. proximal promoter region contains cis-acting elements required for expression in cancer cells PMID: 12890556

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Protein Families
V-ATPase C subunit family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 856

OMIM: 603097

KEGG: hsa:528

STRING: 9606.ENSP00000379203

UniGene: Hs.86905

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