B4GALT3 Antibody

Code CSB-PA00704A0Rb
Size US$166
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  • Western blot
    All lanes: B4GALT3 antibody at 2µg/ml
    Lane 1: EC109 whole cell lysate
    Lane 2: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/15000 dilution
    Predicted band size: 44, 16 kDa
    Observed band size: 44 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA00704A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA00704A0Rb at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) B4GALT3 Polyclonal antibody
Uniprot No.
Target Names
B4GALT3
Alternative Names
4-galactosyltransferase 3 antibody; 4-galactosyltransferase antibody; 4-GalTase 3 antibody; b4Gal T3 antibody; b4Gal-T3 antibody; B4GALT3 antibody; B4GT3_HUMAN antibody; Beta 1,4 galactosyltransferase 3 antibody; Beta 1,4 GalTase 3 antibody; Beta-1 antibody; Beta-N-acetylglucosaminyl-glycolipid beta-1 antibody; Beta4Gal T3 antibody; Beta4Gal-T3 antibody; Nal synthase antibody; UDP Gal:beta GlcNAc beta-1,4 galactosyltransferase 3 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Beta-1,4-galactosyltransferase 3 protein (34-393AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The B4GALT3 Antibody (Product code: CSB-PA00704A0Rb) is Non-conjugated. For B4GALT3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA00704B0Rb B4GALT3 Antibody, HRP conjugated ELISA
FITC CSB-PA00704C0Rb B4GALT3 Antibody, FITC conjugated
Biotin CSB-PA00704D0Rb B4GALT3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
Gene References into Functions
  1. High-metastatic hepatocellular carcinoma cells secrete exosomal miR-1247-3p that directly targets B4GALT3, leading to activation of beta1-integrin-NF-kappaappaB metastatic signaling in fibroblasts resulting in lung cancer. PMID: 29335551
  2. The mutations c.1456C < T (p.L486F) in MYOC and c.322G < A (p.V108I) in B4GALT3 are likely responsible for the pathogenesis of Primary Open-angle Glaucoma in this family. PMID: 27900994
  3. our findings evidenced that B4GALT3 upregulated by miR-27a contributes to the tumorigenic activities by b1-integrin pathway and might provide potential biomarkers for cervical cancer. PMID: 26987623
  4. Data suggest that expression of B4GALT3 in placenta is up-regulated in third trimester; over-expression of B4GALT3 in cultured trophoblasts suppresses cell migration; thus, B4GALT3 appears to regulate trophoblast invasion in late stages of pregnancy. PMID: 25659296
  5. beta-1,4-Galactosyltransferase III suppresses beta1 integrin-mediated invasive phenotypes and negatively correlates with metastasis in colorectal cancer. PMID: 24403309
  6. beta-1,4-Galactosyltransferase III enhances invasive phenotypes via beta1-integrin and predicts poor prognosis in neuroblastoma. PMID: 23444218

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Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.
Protein Families
Glycosyltransferase 7 family
Tissue Specificity
Found in various tissues. Highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain.
Database Links

HGNC: 926

OMIM: 604014

KEGG: hsa:8703

STRING: 9606.ENSP00000320965

UniGene: Hs.321231

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