BHMT2 Antibody

Datasheet

Code	CSB-PA11829A0Rb
Size	US$166
	Order now
Image	Western Blot Positive WB detected in: Mouse liver tissue, Raji whole cell lysate All lanes: BHMT2 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 41, 34 kDa Observed band size: 41, 34 kDa Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA11829A0Rb at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA11829A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) BHMT2 Polyclonal antibody

Uniprot No.

Q9H2M3

Target Names

BHMT2

Alternative Names

BHMT2 antibody; S-methylmethionine--homocysteine S-methyltransferase BHMT2 antibody; SMM-hcy methyltransferase antibody; EC 2.1.1.10 antibody; Betaine--homocysteine S-methyltransferase 2 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human S-methylmethionine--homocysteine S-methyltransferase BHMT2 protein (1-200AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The BHMT2 Antibody (Product code: CSB-PA11829A0Rb) is Non-conjugated. For BHMT2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA11829B0Rb	BHMT2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA11829C0Rb	BHMT2 Antibody, FITC conjugated
Biotin	CSB-PA11829D0Rb	BHMT2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.

Gene References into Functions

Our study suggested markers in BHMT/BHMT2 and DMGDH might affect the risk of NSCL/P through pairwise interaction. PMID: 29356306
A three-way interaction among maternal and fetal variants in BHMT2, GSTP1 and GPX3 contribute to congenital heart defects PMID: 26612412
The faster evolutionary rate of BHMT2 overall suggests that selective constraints were reduced relative to BHMT. PMID: 26213999
Multiple SNPs in BHMT and BHMT2 were identified to be associated with the occurrence of infant obstructive heart defects and interaction effects with maternal use of folic acid supplements. PMID: 25846410
No significant level of association was found with cleft lip with or without cleft palate and BHMT2 variants. PMID: 21564312
gene-gene interaction analysis revealed a significant epistatic interaction of BHMT2 (rs673752), PEMT (rs12325817), and PCYT1A (rs712012) with maternal NCL/P susceptibility. PMID: 20662904
Hyperhomocysteinemia, a risk factor for coronary diseases, can be caused by genetic mutations in BHMT2 metabolism. PMID: 12818402
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. PMID: 18230605
Common genetic variation in BHMT and BHMT2 and functionally characterized BHMT SNPs. PMID: 18457970

Hide All

Tissue Specificity

Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle.

Database Links

HGNC: 1048

OMIM: 605932

KEGG: hsa:23743

STRING: 9606.ENSP00000255192

UniGene: Hs.114172

Promotions

CUSABIO Premium Active Proteins 20% OFF SALE

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address