C16orf62 Antibody

Datasheet

Code	CSB-PA773584HA01HU
Size	US$166
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Image	Immunofluorescent analysis of HepG2 cells using CSB-PA773584HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Western Blot Positive WB detected in: K562 whole cell lysate, Hela whole cell lysate All lanes: C16orf62 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 110, 94 kDa Observed band size: 110 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) C16orf62 Polyclonal antibody

Uniprot No.

Q7Z3J2

Target Names

C16orf62

Alternative Names

C16orf62 antibody; Chromosome 16 open reading frame 62 antibody; CP062_HUMAN antibody; DKFZp313M0539 antibody; DKFZp434B0212 antibody; Esophageal cancer associated protein antibody; Esophageal cancer-associated protein antibody; FLJ21040, antibody; Hypothetical protein LOC57020 antibody; MGC16824 antibody; UPF0505 protein C16orf62 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human UPF0505 protein C16orf62 protein (6-205AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The C16orf62 Antibody (Product code: CSB-PA773584HA01HU) is Non-conjugated. For C16orf62 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA773584HB01HU	C16orf62 Antibody, HRP conjugated	ELISA
FITC	CSB-PA773584HC01HU	C16orf62 Antibody, FITC conjugated
Biotin	CSB-PA773584HD01HU	C16orf62 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability.; (Microbial infection) The heterotrimeric retriever complex, in collaboration with the CCC complex, mediates the exit of human papillomavirus to the cell surface.

Gene References into Functions

Heterotrimer composed of DSCR3, C16orf62 and VPS29 orchestrates endosomal cargo retrieval and recycling. PMID: 28892079

Subcellular Location

Membrane; Single-pass membrane protein. Endosome.

Protein Families

UPF0505 family

Database Links

HGNC: 24641

KEGG: hsa:57020

STRING: 9606.ENSP00000400815

UniGene: Hs.654964

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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