CD2BP2 Antibody

Code CSB-PA001438
Size US$100
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  • Western Blot analysis of COS7 cells using CD2BP2 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CD2BP2
Alternative Names
CD2 (cytoplasmic tail) binding protein 2 antibody; CD2 antigen (cytoplasmic tail) binding protein 2 antibody; CD2 antigen cytoplasmic tail-binding protein 2 antibody; CD2 cytoplasmic domain-binding protein 2 antibody; CD2 tail-binding protein 2 antibody; CD2B2_HUMAN antibody; Cd2bp2 antibody; FWP010 antibody; LIN1 antibody; Snu40 antibody; U5 snRNP 52K protein antibody; U5-52K antibody
Raised in
Rabbit
Species Reactivity
Human,Monkey
Immunogen
Synthesized peptide derived from the Internal region of Human CD2BP2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
Gene References into Functions
  1. Knockdown of CD2BP2 results in reduced miRNA levels. CD2BP2 stabilizes miRISC and mature miRNAs, maintaining them at levels necessary to properly regulate target gene expression. PMID: 28180320
  2. CD2BP2 is the ligand of the membrane-proximal proline-rich tandem repeat of CD2 in detergent-soluble membrane compartments. PMID: 12426371
  3. there is a function of the GYF domain of CD2BP2 in mediating protein-protein interactions within the spliceosome PMID: 15105431
  4. interaction of CD2BP2 with a tri-snRNP bridging protein (Prp6), coupled with CD2BP2's absence from the tri-snRNP, suggests it might function in tri-snRNP assembly PMID: 15840814
  5. findings indicate that CD2BP2 is not a constitutive binding partner or key regulator of CD2-mediated signaling events PMID: 17906334

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Subcellular Location
Cytoplasm. Nucleus. Note=Predominantly nuclear.
Database Links

HGNC: 1656

OMIM: 604470

KEGG: hsa:10421

STRING: 9606.ENSP00000304903

UniGene: Hs.202677

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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