CD2BP2 Antibody

Datasheet

Code	CSB-PA001438
Size	US$119
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Image	Western Blot analysis of COS7 cells using CD2BP2 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O95400

Target Names

CD2BP2

Alternative Names

CD2 (cytoplasmic tail) binding protein 2 antibody; CD2 antigen (cytoplasmic tail) binding protein 2 antibody; CD2 antigen cytoplasmic tail-binding protein 2 antibody; CD2 cytoplasmic domain-binding protein 2 antibody; CD2 tail-binding protein 2 antibody; CD2B2_HUMAN antibody; Cd2bp2 antibody; FWP010 antibody; LIN1 antibody; Snu40 antibody; U5 snRNP 52K protein antibody; U5-52K antibody

Raised in

Rabbit

Species Reactivity

Human,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human CD2BP2.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.

Gene References into Functions

Knockdown of CD2BP2 results in reduced miRNA levels. CD2BP2 stabilizes miRISC and mature miRNAs, maintaining them at levels necessary to properly regulate target gene expression. PMID: 28180320
CD2BP2 is the ligand of the membrane-proximal proline-rich tandem repeat of CD2 in detergent-soluble membrane compartments. PMID: 12426371
there is a function of the GYF domain of CD2BP2 in mediating protein-protein interactions within the spliceosome PMID: 15105431
interaction of CD2BP2 with a tri-snRNP bridging protein (Prp6), coupled with CD2BP2's absence from the tri-snRNP, suggests it might function in tri-snRNP assembly PMID: 15840814
findings indicate that CD2BP2 is not a constitutive binding partner or key regulator of CD2-mediated signaling events PMID: 17906334

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Subcellular Location

Cytoplasm. Nucleus. Note=Predominantly nuclear.

Database Links

HGNC: 1656

OMIM: 604470

KEGG: hsa:10421

STRING: 9606.ENSP00000304903

UniGene: Hs.202677

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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