CDX4 Antibody

Code CSB-PA005129LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: RAW264.7 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, Mouse liver tissue
    All lanes: CDX4 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 31 kDa
    Observed band size: 37 kDa

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA005129LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005129LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDX4 Polyclonal antibody
Uniprot No.
Target Names
CDX4
Alternative Names
Caudal-type homeobox protein 4 antibody; CDX4 antibody; CDX4_HUMAN antibody; Homeobox protein CDX-4 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Homeobox protein CDX-4 protein (16-174AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CDX4 Antibody (Product code: CSB-PA005129LA01HU) is Non-conjugated. For CDX4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005129LB01HU CDX4 Antibody, HRP conjugated ELISA
FITC CSB-PA005129LC01HU CDX4 Antibody, FITC conjugated
Biotin CSB-PA005129LD01HU CDX4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Gene expression analyses on WNT-dependent KDR(+)CD235a(-) definitive hematopoietic mesoderm and WNT-independent KDR(+)CD235a(+) primitive hematopoietic mesoderm revealed strong CDX gene expression within definitive hematopoietic mesoderm. Temporal expression analyses revealed that CDX4 was expressed exclusively within definitive hematopoietic KDR(+)CD235a(-) mesoderm in a WNT- and fibroblast growth factor-dependent manner PMID: 28408465
  2. CDX4 gene was introduced to reprogram adipose tissue derived mesenchymal stem cells to differentiate along the hematopoietic lineage. PMID: 22721648
  3. a molecular mechanisms through which increased expression of HoxA10 increases Cdx4 expression by direct CDX4 activation and by Fgf2-induced beta-catenin activity. This results in Cdx4-induced HoxA10-expression, creating a positive feedback mechanism PMID: 23038246
  4. positive feedback relationship between HoxA10 and Cdx4, which potentially amplified the contribution of either transcription factor to the pathogenesis of AML. PMID: 21471217
Subcellular Location
Nucleus.
Protein Families
Caudal homeobox family
Database Links

HGNC: 1808

OMIM: 300025

KEGG: hsa:1046

STRING: 9606.ENSP00000362613

UniGene: Hs.553488

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