CETN1 Antibody

Datasheet

Code	CSB-PA613263DSR2HU
Size	US$166
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Image	Western blot All lanes: CETN1 antibody at 2.7 μg/ml + Mouse gonadal tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA613263DSR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CETN1 Polyclonal antibody

Uniprot No.

Q12798

Target Names

CETN1

Alternative Names

Caltractin antibody; Caltractin isoform 2 antibody; CEN 1 antibody; CEN1 antibody; Centrin EF hand protein 1 antibody; Centrin-1 antibody; Centrin1 antibody; CETN 1 antibody; CETN antibody; CETN1 antibody; CETN1_HUMAN antibody; EF hand protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Centrin-1 protein (1-172AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays a fundamental role in microtubule-organizing center structure and function. Plays a role in sperm cilia formation.

Gene References into Functions

important spectral and hydrodynamic characteristics of human Centrin-1, accounting that HsCentrin-1 has moderate affinity for Ca(2+). Centrin-1 does not gain structure as seen by far- and near-UV circular dichroism, rather there is a loss of ellipticity, though inconsiderable upon binding Ca(2+). PMID: 27235176
A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin. PMID: 26923803
CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis. PMID: 25261648
These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis. PMID: 16760425

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.

Protein Families

Centrin family

Database Links

HGNC: 1866

OMIM: 603187

KEGG: hsa:1068

STRING: 9606.ENSP00000319052

UniGene: Hs.122511

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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