CETN1 Antibody

Code CSB-PA005264GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CETN1
Alternative Names
Caltractin antibody; Caltractin isoform 2 antibody; CEN 1 antibody; CEN1 antibody; Centrin EF hand protein 1 antibody; Centrin-1 antibody; Centrin1 antibody; CETN 1 antibody; CETN antibody; CETN1 antibody; CETN1_HUMAN antibody; EF hand protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CETN1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a fundamental role in microtubule-organizing center structure and function. Plays a role in sperm cilia formation.
Gene References into Functions
  1. important spectral and hydrodynamic characteristics of human Centrin-1, accounting that HsCentrin-1 has moderate affinity for Ca(2+). Centrin-1 does not gain structure as seen by far- and near-UV circular dichroism, rather there is a loss of ellipticity, though inconsiderable upon binding Ca(2+). PMID: 27235176
  2. A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin. PMID: 26923803
  3. CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis. PMID: 25261648
  4. These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis. PMID: 16760425
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
Protein Families
Centrin family
Database Links

HGNC: 1866

OMIM: 603187

KEGG: hsa:1068

STRING: 9606.ENSP00000319052

UniGene: Hs.122511

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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