CMPK1 Antibody

1. Nuclear CMPK1 expression is indicative of poor prognosis in the triple negative breast cancer patients. PMID: 27558661
2. TGF-b1 inhibited the expression of CMPK, which was blocked in the presence of a TGF-b type I receptor, SB431542, and was abolished by the inhibitor of miR-130b-3p, indicating that CMPK is regulated by the TGF-b signalling pathway through the upregulation of miR-130b-3p. PMID: 28414100
3. The role of CMP/UMP kinase (CMPK), an enzyme catalyzes cytidine diphosphate formation, in DNA repair, was investigated. PMID: 25659034
4. CMPK1 and RBP3 are associated with corneal curvature in Asian populations. PMID: 24963161
5. In particular, polymorphisms of the CMPK1 gene seem to provide important prognostic information PMID: 22838950
6. Single-nucleotide polymorphisms in CMPK1 gene is associated with treatment response in non-small cell lung cancer. PMID: 21642870
7. UMP/CMP kinase (EC 2.7.4.14) is not critical for the phosphorylation of CMP, dCMP and maintenance of natural nucleotide pools in cells PMID: 21559290
8. thymidylate synthase/ribonucleotide reductase gene silencing and deoxycytidine kinase::uridine monophosphate kinase fusion gene gene overexpression markedly improved gemcitabine's therapeutic activity PMID: 19568409
9. Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. PMID: 11912132
10. UMP/CMP kinase reveals the conformational changes that occur upon substrate binding PMID: 15163660
11. Models for the phosphorylation action and substrate specificity of human UMP/CMP kinase. PMID: 15550676
12. Several uracil vinylphosphonate derivatives had affinities for human UMP-CMP kinase similar to those of dUMP PMID: 17608725

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HGNC: 18170

OMIM: 191710

KEGG: hsa:51727

STRING: 9606.ENSP00000360939

UniGene: Hs.731647