CNKSR3 Antibody

1. SCAF8-CNKSR3 variant rs955333 was not associated with diabetic kidney disease but showed association with diabetic retinopathy in Chinese type 2 diabetes patients PMID: 28401168
2. Cox regression and Kaplan-Meier survival analysis identified that amplification of the CNKSR3 gene (log-rank, P = 0.022) with an associated increase in its protein expression (log-rank, P = 0.011) correlated with longer patient survival. PMID: 23357503
3. CNK3 is a molecular scaffold, which coordinates the assembly of a multiprotein ENaC-regulatory complex and hence plays a central role in Na(+) homeostasis. PMID: 22851176
4. two gene markers (CNKSR3 and SPTBN2) differentiate between aspirin-exacerbated respiratory disease and aspirin-tolerant asthma with a perfect discriminative power PMID: 22457146
5. CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration. PMID: 22085542
6. CNKSR3, a homologue of scaffold proteins involved in MAPK pathway regulation, is a direct target of MR and is required for the maintenance of transepithelial sodium transport in the kidney. PMID: 19567370

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HGNC: 23034

OMIM: 617476

KEGG: hsa:154043

STRING: 9606.ENSP00000356182

UniGene: Hs.16064