COG1 Antibody

Code CSB-PA005705GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
COG1
Alternative Names
COG1 antibody; KIAA1381 antibody; LDLBConserved oligomeric Golgi complex subunit 1 antibody; COG complex subunit 1 antibody; Component of oligomeric Golgi complex 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human COG1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for normal Golgi function.
Gene References into Functions
  1. This study reports a novel set of Dengue virus (DENV) NS1-interacting host cell proteins in the HepG2 cell line and proposes possible roles for human NEK2, TAO1, and COG1 in DENV infection. PMID: 27108190
  2. Chronic renal patients with more atherogenic lipoprotein LDL B phenotype are in advanced state of oxidative stress compared with control subjects. PMID: 27412679
  3. Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp PMID: 11929878
  4. These findings support the proposal that COG is directly involved in controlling vesicular retrograde transport of Golgi resident proteins throughout the Golgi apparatus. PMID: 16857184
  5. A novel mutation in COG1 was found in two patients with a cerebrocostomandibular-like syndrome. PMID: 19008299

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Involvement in disease
Congenital disorder of glycosylation 2G (CDG2G)
Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
COG1 family
Database Links

HGNC: 6545

OMIM: 606973

KEGG: hsa:9382

STRING: 9606.ENSP00000299886

UniGene: Hs.103555

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