COG8 Antibody

Code CSB-PA005712GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
COG8
Alternative Names
COG8 antibody; Conserved oligomeric Golgi complex subunit 8 antibody; COG complex subunit 8 antibody; Component of oligomeric Golgi complex 8 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human COG8
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for normal Golgi function.
Gene References into Functions
  1. The exome sequencing was performed to screen all CDG type II-related genes, and two novel frameshift mutations were found: c.171dupG (p.Leu58Alafs*29) and c.1656dupC (p.Ala553Argfs*15) in COG8. PMID: 28619360
  2. TMED6-COG8 chimera might act as a novel diagnostic marker in TFE3 translocation renal cell carcinoma. PMID: 26045774
  3. wthe origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process. PMID: 21805148
Involvement in disease
Congenital disorder of glycosylation 2H (CDG2H)
Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein.
Protein Families
COG8 family
Database Links

HGNC: 18623

OMIM: 606979

KEGG: hsa:84342

STRING: 9606.ENSP00000305459

UniGene: Hs.130849

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