COL19A1 Antibody

Code CSB-PA007137
Size US$100
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Product Details

Uniprot No.
Target Names
COL19A1
Alternative Names
COJA1_HUMAN antibody; COL19A1 antibody; COL9A1L antibody; Collagen alpha-1(XIX) chain antibody; Collagen alpha-1(Y) chain antibody; D6S228E antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human COL19A1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.
Gene References into Functions
  1. Naturally occurring interruptions in nonfibrillar collagen play key roles in molecular flexibility, collagen degradation, and ligand binding. This study focused on a G5G type natural interruption sequence G-POALO-G from human type XIX collagen, a homotrimer collagen, as this sequence possesses distinct properties compared with those of a pathological similar Gly mutation sequence in collagen mimic peptides. PMID: 29376320
  2. Type XIX collagen is a new partner in the interactions between tumor cells and their microenvironment. (Review) PMID: 27491275
  3. collagen IX has unique cell adhesion properties when compared with other collagens, and it provides a novel mechanism for cell adhesion to cartilaginous matrix PMID: 15383545
  4. The NC2 domain of collagen XIX and probably of other FACITs is responsible for chain selection and trimerization PMID: 18845531
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Tissue Specificity
Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
Database Links

HGNC: 2196

OMIM: 120165

KEGG: hsa:1310

STRING: 9606.ENSP00000316030

UniGene: Hs.444842

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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