DCAF6 Antibody

Code CSB-PA011807GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
DCAF6
Alternative Names
1200006M05Rik antibody; Androgen receptor complex associated protein antibody; Androgen receptor complex-associated protein antibody; ARCAP antibody; DCAF6 antibody; DCAF6_HUMAN antibody; DDB1 and CUL4 associated factor 6 antibody; DDB1- and CUL4-associated factor 6 antibody; IQ motif and WD repeat-containing protein 1 antibody; IQ motif and WD repeats 1 antibody; IQWD1 antibody; MSTP055 antibody; NRIP antibody; Nuclear receptor interaction protein antibody; RP4 745I14.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human IQWD1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Gene References into Functions
  1. High IQWD1 expression is associated with breast cancer. PMID: 24222117
  2. NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2. PMID: 22177699
  3. NRIP interacts with either androgen or glucocorticoid receptors PMID: 15784617
  4. NRIP plays a feed-forward role enhancing androgen receptor (AR)-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation. PMID: 17984071
  5. A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression. PMID: 18673574

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Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.
Database Links

HGNC: 30002

OMIM: 610494

KEGG: hsa:55827

STRING: 9606.ENSP00000356814

UniGene: Hs.435741

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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