DDX46 Antibody

Code CSB-PA006627GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
DDX46
Alternative Names
DDX46 antibody; KIAA0801Probable ATP-dependent RNA helicase DDX46 antibody; EC 3.6.4.13 antibody; DEAD box protein 46 antibody; PRP5 homolog antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human DDX46
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays an essential role in splicing, either prior to, or during splicing A complex formation.
Gene References into Functions
  1. Knockdown of DDX46 inhibited osteosarcoma cell proliferation. PMID: 27697093
  2. DDX46 is critical for ESCC cells proliferation. PMID: 27176873
  3. DDX46 is critical for colorectal cancer (CRC) cell proliferation and is a potential therapeutic target for CRC treatment. PMID: 25680556
  4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: DDX46. PMID: 19902070
  5. characterization of protein associated with the human 17S U2 snRNP and one of its stable subunits, SF3b; results indicate that Prp5 plays an important role in pre-mRNA splicing, acting during or prior to prespliceosome assembly PMID: 12234937
  6. Prp5 forms a bridge between U1 and U2 Small Nuclear Ribonucleoproteins at the time of pre-spliceosome formation PMID: 14713954

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Subcellular Location
Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid-anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.
Protein Families
DEAD box helicase family, DDX46/PRP5 subfamily
Database Links

HGNC: 18681

OMIM: 617848

KEGG: hsa:9879

STRING: 9606.ENSP00000346236

UniGene: Hs.406549

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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