ELMO3 Antibody

Datasheet

Code	CSB-PA846590LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA846590LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA846590LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ELMO3 Polyclonal antibody

Uniprot No.

Q96BJ8

Target Names

ELMO3

Alternative Names

CED 12 antibody; Ced 12 homolog 3 antibody; CED12 antibody; ELMO 3 antibody; ELMO3 antibody; ELMO3_HUMAN antibody; Engulfment and cell motility 3 antibody; Engulfment and cell motility protein 3 antibody; FLJ13824 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Engulfment and cell motility protein 3 protein (464-596AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ELMO3 Antibody (Product code: CSB-PA846590LA01HU) is Non-conjugated. For ELMO3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA846590LB01HU	ELMO3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA846590LC01HU	ELMO3 Antibody, FITC conjugated
Biotin	CSB-PA846590LD01HU	ELMO3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

Gene References into Functions

the silencing of ELMO3 inhibited cell proliferation, invasion, metastasis, and F-actin polymerization, and induced Gap 1 (G1) phase cell cycle arrest, demonstrating that ELMO3 is involved in the processes of growth, invasion and metastasis of Colorectal Cancer PMID: 27999268
The purpose of this study was to asses ELMO3 expression in postoperatively irradiated head and neck squamous cell carcinoma patients. PMID: 28039609
The over-expression of ELMO3 was a potential diagnostic and prognostic marker for non-small cell lung cancer. PMID: 26191257
The present study reports the first characterization of the ELMO3 promoter and suggests a significant role of CDX2 in the basal transcriptional regulation of the intestine-specific expression of ELMO3, possibly through interaction with SP1. PMID: 20127720

Subcellular Location

Cytoplasm.

Database Links

HGNC: 17289

OMIM: 606422

KEGG: hsa:79767

STRING: 9606.ENSP00000377566

UniGene: Hs.377416

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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