GOLGA3 Antibody

Code CSB-PA009646GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GOLGA3
Alternative Names
GOLGA3Golgin subfamily A member 3 antibody; Golgi complex-associated protein of 170 kDa antibody; GCP170 antibody; Golgin-160 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human GOLGA3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Golgi auto-antigen; probably involved in maintaining Golgi structure.
Gene References into Functions
  1. The golgin-160 binds directly to the third intracellular loop of beta1AR and that this binding depends on three basic residues in this loop. PMID: 24566136
  2. Golgi protein golgin160 recruits dynein to Golgi membranes. PMID: 22814606
  3. A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic patient PMID: 20170975
  4. NH2 terminal domain of Golgin 160 has a role in nuclear transport and Golgi apparatus localization PMID: 12130652
  5. results indicate that GCP16 is the acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface PMID: 14522980
  6. Caspase-resistant GOLGA3 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. PMID: 15829563
  7. golgin-160 assosiates in an isoform-specific manner with the Golgi-associated protein PIST PMID: 15951434
  8. GCP60 interacts preferentially with one of the golgin-160 caspase cleavage fragments (residues 140-311). This strong interaction prevented the golgin-160 fragment from accumulating in the nucleus when this fragment and GCP60 were overexpressed. PMID: 16870622
  9. golgin-160 may promote efficient surface delivery of a subset of cargo molecules PMID: 17118120
  10. nuclear translocation of golgin-160-(140-311) is a highly coordinated event regulated not only by cleavage of the golgin-160 head but also by the oxidation state of GCP60 PMID: 17711851

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Subcellular Location
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
Tissue Specificity
Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
Database Links

HGNC: 4426

OMIM: 602581

KEGG: hsa:2802

STRING: 9606.ENSP00000204726

UniGene: Hs.507333

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