GRAP Antibody

Code CSB-PA009883GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GRAP
Alternative Names
Grap antibody; GRAP_HUMAN antibody; GRB2 related adaptor protein antibody; GRB2-related adapter protein antibody; Growth factor receptor bound protein 2 related adaptor protein antibody; MGC64880 antibody; OTTHUMP00000065766 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human GRAP
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. Plays a role in the inner ear and in hearing.
Gene References into Functions
  1. Findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression. PMID: 29364705
  2. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed as a novel component of TGF-beta signaling in cultured human renal tubule cells. PMID: 19836472
  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome. PMID: 15174222
  4. Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation. PMID: 18295596
Subcellular Location
Membrane; Peripheral membrane protein. Cell junction, synapse.
Protein Families
GRB2/sem-5/DRK family
Database Links

HGNC: 4562

OMIM: 604330

KEGG: hsa:10750

STRING: 9606.ENSP00000284154

UniGene: Hs.567416

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