IER2 Antibody

Code CSB-PA01729A0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IER2 Polyclonal antibody
Uniprot No.
Target Names
IER2
Alternative Names
IER2 antibody; ETR101 antibody; PIP92 antibody; Immediate early response gene 2 protein antibody; Protein ETR101 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Immediate early response gene 2 protein (1-223AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The IER2 Antibody (Product code: CSB-PA01729A0Rb) is Non-conjugated. For IER2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA01729B0Rb IER2 Antibody, HRP conjugated ELISA
FITC CSB-PA01729C0Rb IER2 Antibody, FITC conjugated
Biotin CSB-PA01729D0Rb IER2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-binding protein that seems to act as a transcription factor. Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis.
Gene References into Functions
  1. IER2 promoted hepatocellular carcinoma cell adhesion and motility by directly increasing ITGB1 expression and subsequently activating the ITGB1FAKSrcpaxillin signal pathway. PMID: 27840969
  2. results from western blot analysis showed that the activity of the focal adhesion kinase (FAK) can be regulated by IER2. PMID: 26260137
  3. ectopic Ier2 expression promoted the motility and invasiveness of poorly metastatic 1AS pancreatic tumor cells in vitro PMID: 22120713
  4. the functioning of ETR101 as a transcriptional activator for the gene ISYNA1 PMID: 19584537
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
IER family
Tissue Specificity
Expressed in activated T-cells (at protein level). Expression increases in metastatic tumor cells (at protein level).
Database Links

HGNC: 28871

KEGG: hsa:9592

STRING: 9606.ENSP00000292433

UniGene: Hs.501629

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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