INSL4 Antibody

Code CSB-PA003040
Size US$100
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  • Western Blot analysis of HT29 cells using INSL4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
INSL4
Alternative Names
early placenta insulin like peptide (EPIL) antibody; Early placenta insulin like peptide A chain antibody; Early placenta insulin like peptide antibody; Early placenta insulin like peptide B chain antibody; Early placenta insulin-like peptide A chain antibody; EPIL antibody; INSL4 antibody; INSL4_HUMAN antibody; insulin like 4 antibody; insulin like 4 (placenta) antibody; Insulin like peptide 4 antibody; Insulin-like peptide 4 antibody; OTTHUMP00000021025 antibody; Placentin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human INSL4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play an important role in trophoblast development and in the regulation of bone formation.
Gene References into Functions
  1. Report decreased INSL4 gene expression in both the invasive and the noninvasive areas of villous trophoblast in patients with placenta accreta. PMID: 23302396
  2. We identified an INSL4 alternatively spliced mRNA species that encodes putative novel INSL4-like peptides. PMID: 12606452
  3. Expression of the INSL4 gene was doubled in the placenta of the growth-restricted twin compared to the normally grown sibling, suggesting that it may be linked to a higher level of apoptosis and loss of cell viability PMID: 15958731
  4. A tight interaction between HER-2 gene and EPIL in invasive breast cancer cells is probable. PMID: 18035692
Subcellular Location
Secreted.
Protein Families
Insulin family
Tissue Specificity
Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells.
Database Links

HGNC: 6087

OMIM: 600910

KEGG: hsa:3641

STRING: 9606.ENSP00000239316

UniGene: Hs.418506

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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