IRAK1BP1 Antibody

Code CSB-PA048353
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human fetal liver tissue, mouse heart tissue, human testis tissue, Primary antibody: CSB-PA048353(IRAK1BP1 Antibody) at dilution 1/475, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
IRAK1BP1
Alternative Names
ActA binding protein 3 antibody; AIP70 antibody; IKBP1_HUMAN antibody; Interleukin 1 receptor associated kinase 1 binding protein 1 antibody; Interleukin-1 receptor-associated kinase 1-binding protein 1 antibody; IRAK1-binding protein 1 antibody; IRAK1BP1 antibody; Signaling molecule that associates with Pelle-like kinase antibody; SIMPL antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human IRAK1BP1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity.
Gene References into Functions
  1. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 coactivator function of SIMPL. PMID: 17079333
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
IRAK1BP1 family
Database Links

HGNC: 17368

OMIM: 615375

KEGG: hsa:134728

STRING: 9606.ENSP00000358956

UniGene: Hs.656212

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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