KHDRBS2 Antibody

Datasheet

Code	CSB-PA730139LA01HU
Size	US$166
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Image	Western blot All lanes: KHDRBS2 antibody at 7µg/ml Lane 1: K562 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: A431 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA730139LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KHDRBS2 Polyclonal antibody

Uniprot No.

Q5VWX1

Target Names

KHDRBS2

Alternative Names

KH domain containing; RNA binding; signal transduction associated protein 2 antibody; 6330586C16Rik antibody; bA535F17.1 antibody; FLJ38664 antibody; hSLM 1 antibody; hSLM-1 antibody; KH domain containing; RNA binding; signal transduction associated 2 antibody; KH domain-containing antibody; KHDR2_HUMAN antibody; khdrbs2 antibody; MGC26664 antibody; RNA-binding antibody; Sam68 like mammalian protein 1 antibody; Sam68-like mammalian protein 1 antibody; signal transduction-associated protein 2 antibody; SLM 1 antibody; SLM-1 antibody; SLM1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KHDRBS2 Antibody (Product code: CSB-PA730139LA01HU) is Non-conjugated. For KHDRBS2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA730139LB01HU	KHDRBS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA730139LC01HU	KHDRBS2 Antibody, FITC conjugated
Biotin	CSB-PA730139LD01HU	KHDRBS2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

Gene References into Functions

molecular cloning and characterization PMID: 12549823

Subcellular Location

Nucleus.

Protein Families

KHDRBS family

Tissue Specificity

Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.

Database Links

HGNC: 18114

OMIM: 610487

KEGG: hsa:202559

STRING: 9606.ENSP00000281156

UniGene: Hs.519794

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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