KHDRBS2 Antibody

Code CSB-PA730139LA01HU
Size US$166
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  • Western blot
    All lanes: KHDRBS2 antibody at 7µg/ml
    Lane 1: K562 whole cell lysate
    Lane 2: Hela whole cell lysate
    Lane 3: A431 whole cell lysate
    Lane 4: Jurkat whole cell lysate
    Lane 5: NIH/3T3 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 39 kDa
    Observed band size: 39 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA730139LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KHDRBS2 Polyclonal antibody
Uniprot No.
Target Names
KHDRBS2
Alternative Names
KH domain containing; RNA binding; signal transduction associated protein 2 antibody; 6330586C16Rik antibody; bA535F17.1 antibody; FLJ38664 antibody; hSLM 1 antibody; hSLM-1 antibody; KH domain containing; RNA binding; signal transduction associated 2 antibody; KH domain-containing antibody; KHDR2_HUMAN antibody; khdrbs2 antibody; MGC26664 antibody; RNA-binding antibody; Sam68 like mammalian protein 1 antibody; Sam68-like mammalian protein 1 antibody; signal transduction-associated protein 2 antibody; SLM 1 antibody; SLM-1 antibody; SLM1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The KHDRBS2 Antibody (Product code: CSB-PA730139LA01HU) is Non-conjugated. For KHDRBS2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA730139LB01HU KHDRBS2 Antibody, HRP conjugated ELISA
FITC CSB-PA730139LC01HU KHDRBS2 Antibody, FITC conjugated
Biotin CSB-PA730139LD01HU KHDRBS2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
Gene References into Functions
  1. molecular cloning and characterization PMID: 12549823
Subcellular Location
Nucleus.
Protein Families
KHDRBS family
Tissue Specificity
Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
Database Links

HGNC: 18114

OMIM: 610487

KEGG: hsa:202559

STRING: 9606.ENSP00000281156

UniGene: Hs.519794

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