KIFC3 Antibody

Code CSB-PA012350GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
KIFC3
Alternative Names
DKFZp686D23201 antibody; FLJ34694 antibody; Kifc3 antibody; KIFC3_HUMAN antibody; Kinesin family member C3 antibody; Kinesin-like protein KIFC3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human KIFC3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance.
Gene References into Functions
  1. Data indicate that E-cadherin ubiquitination consistently increases after depletion of kinesin-like protein KIFC3 or ubiquitin-specific protease USP47. PMID: 25253721
  2. KIFC3 may guide free microtubules to their destination at the bridge and/or may slide and crosslink central bridge microtubules in order to stage the cells for abscission. PMID: 24275865
  3. KifC3 may play a regulatory role in minus-end directed peroxisomal transport for example by blocking the motor function of dynein at peroxisomes. PMID: 23954441
  4. High expression of KIFC3 is associated with docetaxel resistance in breast cancer. PMID: 19789344
Subcellular Location
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle membrane; Peripheral membrane protein.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Database Links

HGNC: 6326

OMIM: 604535

KEGG: hsa:3801

STRING: 9606.ENSP00000368976

UniGene: Hs.23131

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