KIZ Antibody

Datasheet

Code	CSB-PA644808ESR2HU
Size	US$166
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Image	Western blot All lanes: KIZ antibody at 2.89µg/ml Lane 1: HepG2 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: CEM whole cell lysate Lane 4: Hela whole cell lysate Lane 5: Jurkat whole cell lysate Lane 6: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 76, 63, 70, 74, 60 kDa Observed band size: 76 kDa Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA644808ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA644808ESR2HU at dilution of 1:100
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KIZ Polyclonal antibody

Uniprot No.

Q2M2Z5

Target Names

KIZ

Alternative Names

Centrosomal protein kizuna antibody; DKFZP586H021 antibody; HT013 antibody; Kiz antibody; KIZ_HUMAN antibody; KIZUNA antibody; MGC102941 antibody; MGC141930 antibody; NCRNA00153 antibody; Plk1s1 antibody; Polo-like kinase 1 substrate 1 antibody; Uncharacterized protein C20orf19 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Centrosomal protein kizuna protein (1-240AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.

Gene References into Functions

Kiz phosphorylation depends on a balance between CDC25B and Plk1 activities. PMID: 25558830
Immunohistology revealed KIZ localization at the basal body of the cilia in human fibroblasts, thus shedding light on another ciliary protein implicated in autosomal-recessive RCD PMID: 24680887

Involvement in disease

Retinitis pigmentosa 69 (RP69)

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.

Protein Families

Kizuna family

Database Links

HGNC: 15865

OMIM: 615757

KEGG: hsa:55857

UniGene: Hs.187635

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Email: [email protected]
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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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