LRCH1 Antibody

Code CSB-PA897471LA01HU
Size US$166
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  • Western blot
    All lanes: LRCH1 antibody at 15µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 81, 78, 85 kDa
    Observed band size: 81 kDa

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA897471LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA897471LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
Uniprot No.
Target Names
LRCH1
Alternative Names
LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LRCH1 Antibody (Product code: CSB-PA897471LA01HU) is Non-conjugated. For LRCH1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA897471LB01HU LRCH1 Antibody, HRP conjugated ELISA
FITC CSB-PA897471LC01HU LRCH1 Antibody, FITC conjugated
Biotin CSB-PA897471LD01HU LRCH1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
Gene References into Functions
  1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
  2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
  3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
  4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
Subcellular Location
Cytoplasm.
Database Links

HGNC: 20309

OMIM: 610368

KEGG: hsa:23143

STRING: 9606.ENSP00000374447

UniGene: Hs.507971

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