MAB21L2 Antibody

Code CSB-PA896901LA01HU
Size US$166
Order now
Image
  • Western Blot
    Positive WB detected in: Mouse liver tissue
    All lanes: MAB21L2 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 41 kDa
    Observed band size: 41 kDa

  • Immunofluorescent analysis of Hela cells using CSB-PA896901LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAB21L2 Polyclonal antibody
Uniprot No.
Target Names
MAB21L2
Alternative Names
MAB21L2 antibody; Protein mab-21-like 2 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Protein mab-21-like 2 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MAB21L2 Antibody (Product code: CSB-PA896901LA01HU) is Non-conjugated. For MAB21L2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA896901LB01HU MAB21L2 Antibody, HRP conjugated ELISA
FITC CSB-PA896901LC01HU MAB21L2 Antibody, FITC conjugated
Biotin CSB-PA896901LD01HU MAB21L2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

To generate the MAB21L2 polyclonal antibody, the recombinant human MAB21L2 protein (1-300aa) is used to immunize a rabbit. The rabbit's immune system will recognize the immunogen as foreign and produce antibodies against it. After several rounds of immunization, blood is collected from the rabbit and the serum is isolated. The MAB21L2 polyclonal antibodies are purified from the rabbit's serum using protein G affinity chromatography. The purity of this MAB21L2 antibody is 95%+. This MAB21L2 antibody can be used to detect human and mouse MAB21L2 proteins in ELISA, WB, and IF applications.

The MAB21L2 protein is a transcription factor that is involved in regulating the development of various tissues and organs in the body. Specifically, it plays a role in eye development, neural tube closure, and kidney development. Mutations in the MAB21L2 gene can lead to renal disorders and affect cell proliferation and differentiation in other tissues.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Required for several aspects of embryonic development including normal development of the eye.
Gene References into Functions
  1. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
  2. The two unrelated individuals with a novel oculo-skeletal syndrome with intellectual disability described are heterozygous carriers of the same de novo missense mutation c.151C > T (p.Arg51Cys) in MAB21L2. PMID: 26116559
  3. These findings support the identification of MAB21L2 as a novel factor involved in human coloboma and highlight the power of genome editing manipulation in model organisms for analysis of the effects of whole exome variation in humans. PMID: 25719200
  4. This report provides compelling human genomic and genetic evidence that mutations in MAB21L2 cause major eye malformations. PMID: 24906020
Involvement in disease
Microphthalmia/coloboma and skeletal dysplasia syndrome (MCSKS)
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Mab-21 family
Database Links

HGNC: 6758

OMIM: 604357

KEGG: hsa:10586

STRING: 9606.ENSP00000324701

UniGene: Hs.584852

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*