MED24 Antibody

Code CSB-PA177132
Size US$297
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  • Western blot analysis of extracts from 293 cells, using MED24 antibody.
  • Immunofluorescence analysis of HUVEC cells, using MED24 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MED24 Polyclonal antibody
Uniprot No.
Target Names
MED24
Alternative Names
CRSP complex subunit 4 antibody; Activator recruited cofactor 100 kDa component antibody; Activator-recruited cofactor 100 kDa component antibody; ARC100 antibody; Cofactor required for Sp1 transcriptional activation subunit 4 antibody; CRSP complex subunit 4 antibody; CRSP100 antibody; CRSP4 antibody; DRIP100 antibody; hTRAP100 antibody; KIAA0130 antibody; MED 24 antibody; MED24 antibody; MED24_HUMAN antibody; Mediator complex subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 homolog antibody; MGC8748 antibody; OTTHUMP00000164458 antibody; OTTHUMP00000164460 antibody; THRAP4 antibody; Thyroid hormone receptor associated protein 4 antibody; Thyroid hormone receptor associated protein complex 100 kDa component antibody; Thyroid hormone receptor-associated protein 4 antibody; Thyroid hormone receptor-associated protein complex 100 kDa component antibody; Trap100 antibody; Trapp100 antibody; Vitamin D3 receptor interacting protein complex component DRIP100 antibody; Vitamin D3 receptor-interacting protein complex 100 kDa component antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human MED24.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Gene References into Functions
  1. this study shows that haplotypes consisting of single nucleotide polymorphisms harboring PSMD3, CSF3 and MED24 genes are associated with asthma in Slovenian patients PMID: 27163155
  2. Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24, and PSMD3 in European continent (EA) subjects. PMID: 22037903
Subcellular Location
Nucleus.
Protein Families
Mediator complex subunit 24 family
Tissue Specificity
Ubiquitous. Abundant in skeletal muscle, heart and placenta.
Database Links

HGNC: 22963

OMIM: 607000

KEGG: hsa:9862

STRING: 9606.ENSP00000377686

UniGene: Hs.462983

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