METTL1 Antibody

Code CSB-PA013723GA01HU
Size $600
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
METTL1
Alternative Names
C12orf1 antibody; D1075 like gene product antibody; FLJ95748 antibody; Methyltransferase like 1 antibody; Methyltransferase like protein 1 antibody; Methyltransferase-like protein 1 antibody; Mettl1 antibody; TRM8 antibody; TRMB_HUMAN antibody; TRMT8 antibody; tRNA (guanine N(7) ) methyltransferase antibody; tRNA (guanine(46)-N(7))-methyltransferase antibody; tRNA (guanine-N(7)-)-methyltransferase antibody; tRNA(m7G46) methyltransferase antibody; tRNA(m7G46)-methyltransferase antibody; YDL201w antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human METTL1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Methyltransferase that mediates the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs). Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Also acts as a methyltransferase for a subset of internal N(7)-methylguanine in mRNAs. Internal N(7)-methylguanine methylation of mRNAs regulates translation. Also methylates a specific subset of miRNAs, such as let-7. N(7)-methylguanine methylation of let-7 miRNA promotes let-7 miRNA processing by disrupting an inhibitory secondary structure within the primary miRNA transcript (pri-miRNA). Acts as a regulator of embryonic stem cell self-renewal and differentiation.
Gene References into Functions
  1. tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cells PMID: 25233213
Subcellular Location
Nucleus.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, TrmB family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 7030

OMIM: 604466

KEGG: hsa:4234

STRING: 9606.ENSP00000314441

UniGene: Hs.42957

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*