MTHFS Antibody

Datasheet

Code	CSB-PA015159LA01HU
Size	US$166
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Image	Western blot All lanes: MTHFS antibody at 2µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 24, 21 kDa Observed band size: 24 kDa Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA015159LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA015159LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MTHFS Polyclonal antibody

Uniprot No.

P49914

Target Names

MTHFS

Alternative Names

10-methenyl-tetrahydrofolate synthetase antibody; 5 10 methenyl tetrahydrofolate synthetase antibody; 5 antibody; 5 formyltetrahydrofolate cyclo ligase antibody; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) antibody; 5-formyltetrahydrofolate cyclo-ligase antibody; FLJ30410 antibody; HsT19268 antibody; Methenyl THF synthetase antibody; Methenyl-THF synthetase antibody; MTHFS antibody; MTHFS_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 5-formyltetrahydrofolate cyclo-ligase protein (2-203AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MTHFS Antibody (Product code: CSB-PA015159LA01HU) is Non-conjugated. For MTHFS Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA015159LB01HU	MTHFS Antibody, HRP conjugated	ELISA
FITC	CSB-PA015159LC01HU	MTHFS Antibody, FITC conjugated
Biotin	CSB-PA015159LD01HU	MTHFS Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.

Gene References into Functions

The intronic Single nucleotide polymorphism in MTHFS had no significant effect on the risk of diabetic nephropathy in Taiwanese patients with T2D. PMID: 21895484
Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation PMID: 12764149

Subcellular Location

Cytoplasm.

Protein Families

5-formyltetrahydrofolate cyclo-ligase family

Database Links

HGNC: 7437

OMIM: 604197

KEGG: hsa:10588

STRING: 9606.ENSP00000258874

UniGene: Hs.194294

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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