NOSTRIN Antibody

Code CSB-PA015948GA01HU
Size $600
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
NOSTRIN
Alternative Names
BM247 antibody; BM247 homolog antibody; DaIP2 antibody; eNOS-trafficking inducer antibody; mDaIP2 antibody; MGC20702 antibody; Nitric oxide synthase traffic inducer antibody; Nitric oxide synthase trafficker antibody; NOSTN_HUMAN antibody; Nostrin antibody; RP23-431D4.2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NOSTRIN
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Gene References into Functions
  1. The suggest that scores obtained with the worst nostril are the most efficient in detecting an olfactory disorder. PMID: 28981819
  2. NOSTRIN inhibited production of nitric oxide (NO) by suppressing the activation of endothelial nitric oxide synthase (eNOS). PMID: 27401251
  3. no significant difference in serum level associated with preeclampsia or intrauterine growth restriction PMID: 24588201
  4. This study showed that overexpression of NOSTRIN had a significant effect on eNOS activity in HUVECs and resulted in significant cellular damage. PMID: 23592143
  5. The expression of NOSTRIN is decreased, while the activity of eNOS and the level of NO2-/NO3- increased in the testis tissue of azoospermia patients. PMID: 21351530
  6. Results reveal an elegant mechanism of eNOS regulation by PECAM-1 through signal transducers and activators of transcription 3-mediated transcriptional control of NOSTRIN. PMID: 21183735
  7. NOSTRIN expression was increased in umbilical vessel of women with pre-eclampsia. PMID: 19399414
  8. NOSTRIN modulates nitric oxide release and subcellular distribution of endothelial nitric oxide synthase. PMID: 12446846
  9. NOSTRIN may facilitate endocytosis of endothelial nitric oxide synthase by coordinating the function of dynamin and the actin nucleation promoting factor N-WASP. PMID: 16234328
  10. A ternary complex between NOSTRIN, caveolin-1, and eNOS mediates translocation of eNOS, with important implications for the activity and availability of eNOS in the cell. PMID: 16807357
  11. results suggest that nuclear NOSTRINbeta may negatively regulate transcription of the NOSTRIN gene PMID: 18980613

Show More

Hide All

Subcellular Location
[Isoform 1]: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures (PubMed:16234328, PubMed:16376344).; [Isoform 3]: Nucleus.
Tissue Specificity
Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level).
Database Links

HGNC: 20203

OMIM: 607496

KEGG: hsa:115677

UniGene: Hs.189780

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*