NUBPL Antibody

Code CSB-PA819450LA01HU
Size US$166
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  • Western blot
    All lanes: NUBPL antibody at 1µg/ml + A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 35, 19 kDa
    Observed band size: 35 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA819450LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA819450LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUBPL Polyclonal antibody
Uniprot No.
Target Names
NUBPL
Alternative Names
C14orf127 antibody; FLJ12660 antibody; huInd1 antibody; IND1 homolog antibody; Iron-sulfur protein NUBPL antibody; Nubpl antibody; NUBPL_HUMAN antibody; nucleotide binding protein like antibody; Nucleotide-binding protein-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Iron-sulfur protein NUBPL protein (39-319AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NUBPL Antibody (Product code: CSB-PA819450LA01HU) is Non-conjugated. For NUBPL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA819450LB01HU NUBPL Antibody, HRP conjugated ELISA
FITC CSB-PA819450LC01HU NUBPL Antibody, FITC conjugated
Biotin CSB-PA819450LD01HU NUBPL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits.
Gene References into Functions
  1. huInd1 binds to the untranslated region of the TEM-1 mRNA at 3' site and thereby reducing the possibility of its endonucleolytic cleavage, resulting in over-expression of TEM-1. PMID: 25240856
  2. Inhibition of ERK suppressed the NUBPL-induced changes in EMT and cell motility. PMID: 28346728
  3. Our data show that NUBPL mutations are associated with a unique, consistent, and recognizable MRI pattern. PMID: 23553477
  4. Mutations in NUBPL is associated with complex I deficiency. PMID: 20818383
  5. These data identify huInd1 as a new assembly factor for human respiratory complex I with a possible role in the delivery of one or more Fe/S clusters to complex I subunits.[Ind1] PMID: 19752196

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Involvement in disease
Mitochondrial complex I deficiency (MT-C1D)
Subcellular Location
Mitochondrion.
Protein Families
Mrp/NBP35 ATP-binding proteins family
Tissue Specificity
Highest expression in liver and kidney. expressed at significant levels in small intestine and brain (at protein level).
Database Links

HGNC: 20278

OMIM: 252010

KEGG: hsa:80224

STRING: 9606.ENSP00000281081

UniGene: Hs.288981

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