OXR1 Antibody

Datasheet

Code	CSB-PA854043LA01HU
Size	US$166
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Image	Western blot All lanes: OXR1 antibody at 1µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 98, 94, 56, 28, 95, 34, 25 kDa Observed band size: 90 kDa Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA854043LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA854043LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) OXR1 Polyclonal antibody

Uniprot No.

Q8N573

Target Names

OXR1

Alternative Names

C7 antibody; C7B antibody; Gm1238 antibody; Nbla00307 antibody; Nucleolar protein C7 antibody; Oxidation resistance 1 antibody; Oxidation resistance protein 1 antibody; Oxr1 antibody; OXR1_HUMAN antibody; Putative protein product of Nbla00307 antibody; rCG_59825 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Oxidation resistance protein 1 protein (401-600AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The OXR1 Antibody (Product code: CSB-PA854043LA01HU) is Non-conjugated. For OXR1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA854043LB01HU	OXR1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA854043LC01HU	OXR1 Antibody, FITC conjugated
Biotin	CSB-PA854043LD01HU	OXR1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May be involved in protection from oxidative damage.

Gene References into Functions

OXR1 may act as a sensor of cellular oxidative stress to regulate the transcriptional networks required to detoxify reactive oxygen species and modulate cell cycle and apoptosis. PMID: 26616534
Oxr1 serves as a potential therapeutic target for ALS and other neurodegenerative disorders characterized by TDP-43 or FUS pathology. PMID: 25792726
OXR1 upregulates the expression of antioxidant genes via the p21 signaling pathway to suppress hydrogen peroxide-induced oxidative stress and maintain mtDNA integrity. PMID: 25236744
The protein segment encoded by exon 8 plays an important role in the anti-oxidative function of the human OXR1 protein. PMID: 22873401
Data show that human and yeast oxidation resistance 1 (OXR1) genes are induced by heat and oxidative stress and that their proteins localize to the mitochondria and function to protect against oxidative damage. PMID: 15060142
human OXR1 is capable of reducing the DNA damaging effects of reactive oxygen species when expressed in bacteria, indicating the protein has an activity that can contribute to oxidation resistance. PMID: 17391516

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Subcellular Location

Mitochondrion.

Protein Families

OXR1 family

Database Links

HGNC: 15822

OMIM: 605609

KEGG: hsa:55074

STRING: 9606.ENSP00000405424

UniGene: Hs.127286

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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