PAGE4 Antibody

Datasheet

Code	CSB-PA900712
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA900712(PAGE4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

O60829

Target Names

PAGE4

Alternative Names

PAGE4 antibody; GAGEC1 antibody; JM27P antigen family member 4 antibody; PAGE-4 antibody; G antigen family C member 1 antibody; PAGE-1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human PAGE4

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Intrinsically disordered protein that potentiates the transcriptional activator activity of JUN. Protects cells from stress-induced apoptosis by inhibiting reactive oxygen species (ROS) production and via regulation of the MAPK signaling pathway.

Gene References into Functions

phosphorylation of PAGE4 leads to conformational shifts PMID: 26242913
PAGE4, a regulator of c-Jun transactivation, is phosphorylated by homeodomain-interacting protein kinase 1. PMID: 24559171
Data suggest that disrupting prostate-associated gene 4 (PAGE4)/c-Jun interaction using small molecules could be a novel strategy to treat prostate cancer. PMID: 24263171
Dysregulation of epithelial PAGE4 modulates AR signaling. PMID: 22885105
PAGE4 is a highly intrinsically disordered protein with an anti-apoptotic function PMID: 21357425
PAGE4 mRNA is expressed only in the cytoplasm of epithelial cells of normal and prostate-cancer specimens PMID: 12489849
These results suggest that GAGE gene might have an important role in the development and progression of intestinal type of stomach cancer and the detection of GAGE mRNA may be eligible to the panel of molecular markers for aggressive behavior. PMID: 15362791

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Subcellular Location

Cytoplasm. Nucleus. Mitochondrion.

Protein Families

GAGE family

Tissue Specificity

Expressed at basal lvels in the adult normal prostate gland but is highly up-regulated in the fetal prostate and prostate cancer cells. Preferentially expressed in normal male and female reproductive tissues, testis, fallopian tube, uterus, and placenta,

Database Links

HGNC: 4108

OMIM: 300287

KEGG: hsa:9506

STRING: 9606.ENSP00000218068

UniGene: Hs.441038

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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