PASD1 Antibody

Datasheet

Code	CSB-PA816882LA01HU
Size	US$166
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Image	Western blot All lanes: PASD1 antibody at 4µg/ml + A549 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 88, 73 kDa Observed band size: 88 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PASD1 Polyclonal antibody

Uniprot No.

Q8IV76

Target Names

PASD1

Alternative Names

Cancer/testis antigen 63 antibody; CT63 antibody; OX-TES-1 antibody; PAS domain containing 1 antibody; PAS domain-containing protein 1 antibody; PASD1 antibody; PASD1_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Circadian clock protein PASD1 protein (301-600AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PASD1 Antibody (Product code: CSB-PA816882LA01HU) is Non-conjugated. For PASD1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA816882LB01HU	PASD1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA816882LC01HU	PASD1 Antibody, FITC conjugated
Biotin	CSB-PA816882LD01HU	PASD1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed.

Gene References into Functions

PASD1 serves as a critical nuclear positive regulator of STAT3-mediated gene expression and tumorigenesis. PMID: 26892021
PASD1 is a circadian bHLH-PAS paralog repressor of CLOCK protein expression. PMID: 25936801
PASD1-derived epitopes are both efficiently and selectively processed and presented by native human multiple myeloma cells as cancer vaccines. PMID: 20861911

Subcellular Location

[Isoform 1]: Nucleus.; [Isoform 2]: Nucleus.

Tissue Specificity

Testis-specific. Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widesp

Database Links

HGNC: 20686

OMIM: 300993

KEGG: hsa:139135

STRING: 9606.ENSP00000359382

UniGene: Hs.160594

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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CT83/KK-LC-1: a Promising Therapeutic Target of CTAs Family, Currently in Clinical Research for Breast, Lung, Gastric Cancers, and Beyond! Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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