PMPCA Antibody

Code CSB-PA606021ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA606021ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA606021ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PMPCA Polyclonal antibody
Uniprot No.
Target Names
PMPCA
Alternative Names
1200002L24Rik antibody; 4933435E07Rik antibody; Alpha MPP antibody; Alpha-MPP antibody; FLJ26258 antibody; Inositol polyphosphate 5 phosphatase, 72 kD antibody; INPP5E antibody; KIAA0123 antibody; MGC104197 antibody; MGC93916 antibody; Mitochondrial matrix processing protease, alpha subunit antibody; mitochondrial processing peptidase subunit alpha antibody; Mitochondrial-processing peptidase subunit alpha antibody; MPPA_HUMAN antibody; P 55 antibody; P-55 antibody; Peptidase (mitochondrial processing) alpha antibody; pmpca antibody; RP11-413M3.1 antibody; RP23-306D20.8 antibody; SCAR2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mitochondrial-processing peptidase subunit alpha protein (456-525AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Gene References into Functions
  1. study represents the first time that defects in PMPCA and mitochondrial processing peptidase have been described in association with a disease phenotype in humans. PMID: 25808372
  2. OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase. PMID: 24903103
Involvement in disease
Spinocerebellar ataxia, autosomal recessive, 2 (SCAR2)
Subcellular Location
Mitochondrion matrix. Mitochondrion inner membrane.
Protein Families
Peptidase M16 family
Tissue Specificity
Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
Database Links

HGNC: 18667

OMIM: 213200

KEGG: hsa:23203

STRING: 9606.ENSP00000360782

UniGene: Hs.495471

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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