POLE2 Antibody

Code CSB-PA004689
Size US$100
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  • Western Blot analysis of Jurkat cells using DNA pol ε B Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
POLE2
Alternative Names
DNA polymerase epsilon subunit 2 antibody; DNA polymerase epsilon subunit B antibody; DNA polymerase II subunit 2 antibody; DPE 2 antibody; DPE2 antibody; DPOE2_HUMAN antibody; POLE 2 antibody; POLE2 antibody; Polymerase (DNA directed) epsilon 2 (p59 subunit) antibody; Polymerase (DNA directed) epsilon 2 antibody; polymerase (DNA directed); epsilon 2; accessory subunit antibody; Polymerase; DNA; epsilon-2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human DNA pol ε B.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
Gene References into Functions
  1. found that mutations occurred in POLE2 in 5 out of 16 cases of human colon cancer examined. PMID: 20065316
  2. The solution structure of the N-terminal domain of human DNA polymerase epsilon subunit B revealed a domain that consists of a left-handed superhelical bundle. PMID: 18676977
Subcellular Location
Nucleus.
Protein Families
DNA polymerase epsilon subunit B family
Database Links

HGNC: 9178

OMIM: 602670

KEGG: hsa:5427

STRING: 9606.ENSP00000216367

UniGene: Hs.162777

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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