POLR2J Antibody

Code CSB-PA030120
Size US$100
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Product Details

Uniprot No.
Target Names
POLR2J
Alternative Names
DNA directed RNA polymerase II subunit RPB11 a antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit J 1 antibody; DNA-directed RNA polymerase II subunit J-1 antibody; DNA-directed RNA polymerase II subunit RPB11-a antibody; hRPB 14 antibody; hRPB14 antibody; POLR 2J1 antibody; POLR2J antibody; POLR2J1 antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; RNA polymerase II 13.3 kDa subunit antibody; RNA polymerase II subunit B11 a antibody; RNA polymerase II subunit B11-a antibody; RPB 11 antibody; RPB 11A antibody; RPB 11m antibody; RPB11 antibody; RPB11_HUMAN antibody; RPB11a antibody; RPB11m antibody; Rpo2-4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of Human POLR2J1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
Gene References into Functions
  1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
  2. Four independent genes(POLR2J1, POLR2J2, POLR2J3, POLR2J4) encoding various variants of the hRPB11 subunit of Homo sapiens RNA polymerase II were revealed in human chromosome 7 PMID: 15586814
Subcellular Location
Nucleus.
Protein Families
Archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
Tissue Specificity
Ubiquitously expressed. High expression was found in heart and skeletal muscle.
Database Links

HGNC: 9197

OMIM: 604150

KEGG: hsa:5439

STRING: 9606.ENSP00000292614

UniGene: Hs.654952

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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