POLR2J Antibody

Code CSB-PA347112LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) POLR2J Polyclonal antibody
Uniprot No.
Target Names
POLR2J
Alternative Names
DNA directed RNA polymerase II subunit RPB11 a antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit J 1 antibody; DNA-directed RNA polymerase II subunit J-1 antibody; DNA-directed RNA polymerase II subunit RPB11-a antibody; hRPB 14 antibody; hRPB14 antibody; POLR 2J1 antibody; POLR2J antibody; POLR2J1 antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; RNA polymerase II 13.3 kDa subunit antibody; RNA polymerase II subunit B11 a antibody; RNA polymerase II subunit B11-a antibody; RPB 11 antibody; RPB 11A antibody; RPB 11m antibody; RPB11 antibody; RPB11_HUMAN antibody; RPB11a antibody; RPB11m antibody; Rpo2-4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human DNA-directed RNA polymerase II subunit RPB11-a protein (1-117AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The POLR2J Antibody (Product code: CSB-PA347112LA01HU) is Non-conjugated. For POLR2J Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA347112LB01HU POLR2J Antibody, HRP conjugated ELISA
FITC CSB-PA347112LC01HU POLR2J Antibody, FITC conjugated
Biotin CSB-PA347112LD01HU POLR2J Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
Gene References into Functions
  1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
  2. Four independent genes(POLR2J1, POLR2J2, POLR2J3, POLR2J4) encoding various variants of the hRPB11 subunit of Homo sapiens RNA polymerase II were revealed in human chromosome 7 PMID: 15586814
Subcellular Location
Nucleus.
Protein Families
Archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
Tissue Specificity
Ubiquitously expressed. High expression was found in heart and skeletal muscle.
Database Links

HGNC: 9197

OMIM: 604150

KEGG: hsa:5439

STRING: 9606.ENSP00000292614

UniGene: Hs.654952

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