Phospho-FAM129A (Ser602) Antibody

Datasheet

Code	CSB-PA589975
Size	US$360
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Image	Western blot analysis in vitro kinase assays were performed by mixing purified bacterially expressed WT His-Niban or the His-Niban S602A with or without purified active AKT1 using Niban (Phospho-Ser602) Antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FAM129A Polyclonal antibody

Uniprot No.

Q9BZQ8

Target Names

FAM129A

Alternative Names

NIBAN1 antibody; C1orf24 antibody; FAM129A antibody; NIBAN antibody; GIG39 antibody; Protein Niban 1 antibody; Cell growth-inhibiting gene 39 protein antibody; Protein FAM129A antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Peptide sequence around phosphorylation site of serine 602 (R-A-S(p)-A-I) derived from Human Niban.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.

Gene References into Functions

Data suggest that decreasing C1orf24 protein levels by restoring microRNA miR-106b function may have therapeutic implications. PMID: 26317551
DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
The expression of Niban frequently begins in the early stages of head and neck squamous carcinoma and remains upregulated throughout the carcinogenic process. Niban may be a good molecular marker of HNSCC. PMID: 19536772
Niban expression is up-regulated in various types of thyroid tumors. PMID: 16949643

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Subcellular Location

Cytoplasm. Membrane; Lipid-anchor.

Protein Families

Niban family

Tissue Specificity

Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with

Database Links

HGNC: 16784

KEGG: hsa:116496

STRING: 9606.ENSP00000356481

UniGene: Hs.518662

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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