RASSF8 Antibody

1. data provide evidence that E4BP4 attenuates RASSF8-mediated anti-proliferation and apoptosis, shedding mechanistic insights into RASSF8 down-regulation in breast cancers. PMID: 29467226
2. MiR-505 mediated MTX resistance, propagation, cell cycle and metastasis by targeting RASSF8 in colorectal cancer PMID: 29726011
3. The miR-224 played an oncogenic role in the proliferation of NSCLC by direct targeting RASSF8. PMID: 28770961
4. RASSF8 knockdown by specific RNAi showed similar effects in cervical cancer cells transfected with miR-224 mimic. Our findings suggest that miR-224 directly targets RASSF8 and thereby acts as a tumor promoter in cervical cancer progression PMID: 27626930
5. These results indicate that hypoxia-inducible miR-224 promotes gastric cancer cell growth, migration and invasion by downregulating RASSF8 and acts as an oncogene, implying that inhibition of miR-224 may have potential as a therapeutic target for patients with hypoxic gastric tumors. PMID: 28173803
6. RASSF8 acts as a tumor suppressor in squamous cell carcinoma PMID: 26439687
7. RASSF8 plays a significant role in suppressing the progression of cutaneous melanoma. PMID: 26334503
8. RASSF8 as a tumor suppressor gene that is essential for maintaining AJs function in epithelial cells and have a role in epithelial cell migration. PMID: 20514026
9. Expression of RASSF8 protein by transfected lung cancer cells led to inhibition of anchorage-independent growth in soft agar in A549 cells and reduction of clonogenic activity in NCI-H520 cells PMID: 16462760

Show More

Hide All

HGNC: 13232

OMIM: 608180

KEGG: hsa:11228

STRING: 9606.ENSP00000282884

UniGene: Hs.696433