RGS18 Antibody

Datasheet

Code	CSB-PA019649LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA019649LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA019649LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody

Uniprot No.

Q9NS28

Target Names

RGS18

Alternative Names

Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RGS18 Antibody (Product code: CSB-PA019649LA01HU) is Non-conjugated. For RGS18 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA019649LB01HU	RGS18 Antibody, HRP conjugated	ELISA
FITC	CSB-PA019649LC01HU	RGS18 Antibody, FITC conjugated
Biotin	CSB-PA019649LD01HU	RGS18 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.

Gene References into Functions

These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
gene mapped to chromosome 1. PMID: 16484797

Subcellular Location

Cytoplasm.

Tissue Specificity

Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.

Database Links

HGNC: 14261

OMIM: 607192

KEGG: hsa:64407

STRING: 9606.ENSP00000356430

UniGene: Hs.440890

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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