RPH3AL Antibody

Code CSB-PA891975DSR1HU
Size US$166
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  • Western blot
    All lanes: RPH3AL antibody at 12μg/ml
    Lane 1: LO2 whole cell lysate
    Lane 2: K562 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 35, 32 kDa
    Observed band size: 35 kDa

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA891975DSR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPH3AL Polyclonal antibody
Uniprot No.
Target Names
RPH3AL
Alternative Names
Gm1753 antibody; No C2 domains protein antibody; Noc2 antibody; Rab effector Noc2 antibody; Rabphilin 3A-like (without C2 domains) antibody; Rabphilin 3A-like antibody; Rabphilin-3A-like protein antibody; RPH3AL antibody; RPH3L_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Rab effector Noc2 protein (161-315AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells.
Gene References into Functions
  1. genetic alterations in RPH3AL are associated with aggressive behavior of breast cancers and with short survival of patients. PMID: 26070152
  2. Mutations of rabphillin-3A-like gene is associated with colorectal cancers PMID: 12375017
  3. Noc2 may function as a Rab3B effector protein in epithelial cells. PMID: 15003533
Subcellular Location
Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
Tissue Specificity
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
Database Links

HGNC: 10296

OMIM: 604881

KEGG: hsa:9501

STRING: 9606.ENSP00000328977

UniGene: Hs.651925

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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