RPH3AL Antibody

Code CSB-PA020103GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RPH3AL
Alternative Names
Gm1753 antibody; No C2 domains protein antibody; Noc2 antibody; Rab effector Noc2 antibody; Rabphilin 3A-like (without C2 domains) antibody; Rabphilin 3A-like antibody; Rabphilin-3A-like protein antibody; RPH3AL antibody; RPH3L_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NOC2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells.
Gene References into Functions
  1. genetic alterations in RPH3AL are associated with aggressive behavior of breast cancers and with short survival of patients. PMID: 26070152
  2. Mutations of rabphillin-3A-like gene is associated with colorectal cancers PMID: 12375017
  3. Noc2 may function as a Rab3B effector protein in epithelial cells. PMID: 15003533
Subcellular Location
Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
Tissue Specificity
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
Database Links

HGNC: 10296

OMIM: 604881

KEGG: hsa:9501

STRING: 9606.ENSP00000328977

UniGene: Hs.651925

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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