RPL15 Antibody

Code CSB-PA040240
Size US$119
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Product Details

Uniprot No.
Target Names
RPL15
Alternative Names
60S ribosomal protein L15 antibody; EC45 antibody; FLJ26304 antibody; ribosomal protein L15 antibody; RL15_HUMAN antibody; RPL10 antibody; RPL15 antibody; RPLY10 antibody; RPYL10 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human Ribosomal Protein L15.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. Aurora kinase inhibitor danusertib negatively regulated AURKB/p70S6K/RPL15 axis with the involvement of PI3K/Akt/mTOR, AMPK, and p38 MAPK signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells. PMID: 27612557
  2. Downregulation of RPL15 is associated with tumor progression in pancreatic ductal adenocarcinoma. PMID: 26498693
  3. These data identify RPL15 as a new gene involved in Diamond-Blackfan anemia. PMID: 23812780
  4. ISG56 interacts with ribosomal protein L15 in gastric cancer cells. PMID: 21612406
  5. RPL15 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
  6. RPL15 promotes cell proliferation in gastric neoplasms PMID: 16608517

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Involvement in disease
Diamond-Blackfan anemia 12 (DBA12)
Subcellular Location
Membrane; Lipid-anchor.
Protein Families
Eukaryotic ribosomal protein eL15 family
Database Links

HGNC: 10306

OMIM: 604174

KEGG: hsa:6138

STRING: 9606.ENSP00000309334

UniGene: Hs.381219

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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