RPL7 Antibody

Datasheet

Code	CSB-PA003997
Size	US$100
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Image	Western Blot analysis of HeLa cells using Ribosomal Protein L7 Polyclonal Antibody Western Blot analysis of customer's(cat sample) using Ribosomal Protein L7 Polyclonal Antibody. Western blot analysis of Mouse-kidney mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using Ribosomal Protein L7 antibody.
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Product Details
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Target Background

Product Details

Uniprot No.

P18124

Target Names

RPL7

Alternative Names

60S ribosomal protein L7 antibody; humL7 1 antibody; L7 antibody; Ribosomal protein L7 antibody; RL7_HUMAN antibody; RPL 7 antibody; RPL7 antibody; Rpl7a antibody; Surf 3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the C-terminal region of Human Ribosomal Protein L7.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the large ribosomal subunit. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.

Gene References into Functions

HIV-1 Gag NC domain interacts with the ribosomal protein RPL7 endowed with nucleic acid chaperone activity, favoring the notion that RPL7 could be a Gag helper chaperoning factor possibly contributing to the start of Gag assembly PMID: 27515235
In case of L7, importin beta2 or importin beta3 are preferentially used by clusters with a high import efficiency. PMID: 23266416
RPL7 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
importin beta3 is essential for the nuclear import of RPL7. The import is mediated via the multifaceted basic amino acid clusters present in the NH(2)-region of RPL7, and is RanGTP-dependent PMID: 20828572
Combining with the phylogenic findings from homologous sequence alignment, the NH2-region of L7, besides being as a eukaryotic expansion segment, can be excluded from building a functional eukaryotic ribosome. PMID: 16797011
L7-endoplasmic reticulum-binding nature could be one of multiple factors that allow a nascent peptide-less ribosome to remain at the endoplasmic reticulum. PMID: 17258209

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Protein Families

Universal ribosomal protein uL30 family

Database Links

HGNC: 10363

OMIM: 604166

KEGG: hsa:6129

STRING: 9606.ENSP00000339795

UniGene: Hs.421257

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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