RPRD1A Antibody

Datasheet

Code	CSB-PA850404LA01HU
Size	US$166
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Image	Western blot All lanes: RPRD1A antibody at 2μg/ml Lane 1: A431 whole cell lysate Lane 2: Jurkat whole cell lysate Secondary Goat polyclonal to Rabbit IgG at 1/10000 dilution Predicted band size: 36, 32 kDa Observed band size: 36 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RPRD1A Polyclonal antibody

Uniprot No.

Q96P16

Target Names

RPRD1A

Alternative Names

C77387 antibody; CDKN2B-related protein antibody; Cyclin dependent kinase 2B inhibitor related protein antibody; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein) antibody; Cyclin dependent kinase inhibitor 2B related protein antibody; Cyclin dependent kinase inhibitor related protein antibody; Cyclin-dependent kinase inhibitor 2B-related protein antibody; FLJ10656 antibody; HsT3101 antibody; Hypothetical protein FLJ10656 antibody; KIAA4077 antibody; MGC19513 antibody; MGC29396 antibody; MGC36325 antibody; mKIAA4077 antibody; p15INK4B related protein antibody; p15INK4B-related protein antibody; Putative uncharacterized protein P15RS antibody; Regulation of nuclear pre mRNA domain containing 1A antibody; Regulation of nuclear pre-mRNA domain-containing protein 1A antibody; RGD1307374 antibody; RPR1A_HUMAN antibody; RPRD1A antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Regulation of nuclear pre-mRNA domain-containing protein 1A protein (2-276AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RPRD1A Antibody (Product code: CSB-PA850404LA01HU) is Non-conjugated. For RPRD1A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA850404LB01HU	RPRD1A Antibody, HRP conjugated	ELISA
FITC	CSB-PA850404LC01HU	RPRD1A Antibody, FITC conjugated
Biotin	CSB-PA850404LD01HU	RPRD1A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.

Gene References into Functions

Data suggest that p15RS (p15INK4b-related sequence) acts as an intrinsic transcriptional repressor for Wnt/beta-catenin-mediated gene transcription through recruiting HDAC2 histone deacetylase. PMID: 25697359
RPRD1A and RPRD1B associate directly with RPAP2 phosphatase and coordinate the dephosphorylation of RNAPII phospho-S5 by RPAP2. PMID: 24997600
The p15RS expression specifically downregulates the expression of cathepsin B and MMP-9 at RNA levels, which are known to promote cell invasion through degrading extracellular matrix proteins. PMID: 22580456
p15RS inhibits Wnt signaling by interrupting beta-catenin.TCF4 complex formation and that Wnt signaling initiates downstream gene expression by removing p15RS from promoters. PMID: 20739273
molecular cloning and characterization of P15RS, a novel P15(INK4b) related gene involved in G1/S progression PMID: 12470661

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Protein Families

UPF0400 (RTT103) family

Database Links

HGNC: 25560

OMIM: 610347

KEGG: hsa:55197

STRING: 9606.ENSP00000349955

UniGene: Hs.464912

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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