RSU1 Antibody

1. our results indicate the important role of RSU-1 in BC metastasis and set the foundations for its validation as potential BC metastasis marker. PMID: 28423706
2. Ras suppressor protein 1 was confirmed to be directly targeted by miR-409-5p in breast cancer cells. Small interfering RNA-mediated Ras suppressor protein 1 inhibition reversely promoted cancer proliferation and migration in miR-409-5p-downregualted breast cancer cells. MiR-409-5p is downregulated in breast cancer and its inhibition has anti-cancer effect on breast cancer development both in vitro and in vivo. PMID: 28459205
3. Rsu1 is required for EGF-induced activation of the p38 map kinase signaling PMID: 25482629
4. integrin/Rsu1/Rac1/actin signaling has a conserved role in modulating reward-related phenotypes, including ethanol consumption, across phyla PMID: 26170296
5. Upregulation of RSU1 is associated with metastatic breast cancer. PMID: 25647720
6. results showed that RSU-1 expression is elevated in HepG2 cells both at the mRNA and protein level PMID: 25750304
7. alternative splicing of exon 8 of the RSU-1 RNA to produce the exon-deleted form constitutes a mechanism for reduction or loss of functional Rsu-1. The exon-deleted form was not found in normal tissue. PMID: 12510772
8. Rsu-1 links the Ras pathway with the IPP (integrin-linked kinase {ILK}, PINCH-1/LIMS1, parvin) complex and the perturbations of cell attachment-dependent signaling that occur in the malignant process PMID: 18436335

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HGNC: 10464

OMIM: 179555

KEGG: hsa:6251

STRING: 9606.ENSP00000339521

UniGene: Hs.524161