SAT2 Antibody

Datasheet

Code	CSB-PA020718GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q96F10

Target Names

SAT2

Alternative Names

Amino acid transporter A2 antibody; ATA2 antibody; Diamine acetyltransferase 2 antibody; Diamine N acetyltransferase 2 antibody; Polyamine N acetyltransferase antibody; Polyamine N-acetyltransferase 2 antibody; Protein 40 9 1 antibody; SAT2 antibody; SAT2_HUMAN antibody; SNAT2 antibody; Solute carrier family 38 member 2 antibody; Spermidine/spermine N(1)-acetyltransferase 2 antibody; Spermidine/spermine N1 acetyltransferase 2 antibody; Spermidine/spermine N1 acetyltransferase family member 2 antibody; SSAT2 antibody; System A amino acid transporter 2 antibody; System A transporter 1 antibody; System N amino acid transporter 2 antibody; Thialysine N-epsilon-acetyltransferase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SAT2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur. May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine. However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo.

Gene References into Functions

Crystallization of this protein and its recombinant form and its complexation with coenzyme A. PMID: 16596569
The expression of three messengers coding for SAT-1, SAT-2 and GalNAcT-1 in human samples of intestinal cancer and some cell lines (breast cancer and melanomas), was evaluated. PMID: 17119850
SSAT2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha PMID: 17558023
SSAT1, which shares 46% amino acid identity with SSAT2, also binds to HIF-1alpha and promotes its ubiquitination/degradation. However, in contrast to SSAT2, SSAT1 acts by stabilizing the interaction of HIF-1alpha with RACK1 PMID: 17875644
expression of SSAT mediated by Ad-SSAT infection inhibits the growth of colorectal cancer cells PMID: 18949426

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Subcellular Location

Cytoplasm.

Protein Families

Acetyltransferase family

Tissue Specificity

Widely expressed. Under physiological conditions, SSAT2 is expressed at lower level that SSAT1 (SSAT). Many tissues express only SSAT1, several tissues express both SSAT1 and SSAT2, and bone, cervix, ovary and pineal gland expressed only SSAT2.

Database Links

HGNC: 23160

OMIM: 611463

KEGG: hsa:112483

STRING: 9606.ENSP00000269298

UniGene: Hs.10846

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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