SCOC Antibody

Datasheet

Code	CSB-PA020854LA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA020854LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA020854LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA020854LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SCOC Polyclonal antibody

Uniprot No.

Q9UIL1

Target Names

SCOC

Alternative Names

HRIHFB2072 antibody; Scoc antibody; SCOC_HUMAN antibody; SCOCO antibody; Short coiled coil protein antibody; Short coiled-coil protein antibody; UNC-69 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Short coiled-coil protein (1-121AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SCOC Antibody (Product code: CSB-PA020854LA01HU) is Non-conjugated. For SCOC Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA020854LB01HU	SCOC Antibody, HRP conjugated	ELISA
FITC	CSB-PA020854LC01HU	SCOC Antibody, FITC conjugated
Biotin	CSB-PA020854LD01HU	SCOC Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Positive regulator of amino acid starvation-induced autophagy.

Gene References into Functions

SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis] PMID: 27023175
SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction. PMID: 24098481
Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process. PMID: 24116125
The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037

Subcellular Location

Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.

Protein Families

SCOC family

Tissue Specificity

Widely expressed with highest levels in brain, heart and skeletal muscle.

Database Links

HGNC: 20335

KEGG: hsa:60592

STRING: 9606.ENSP00000377751

UniGene: Hs.480815

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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