SEPT1 Antibody

Code CSB-PA004067
Size US$119
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  • Western Blot analysis of COLO205 cells using Septin 1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
SEPT1
Alternative Names
DIFF6 antibody; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase) antibody; LARP antibody; MGC20394 antibody; Peanut like protein 3 antibody; Peanut-like protein 3 antibody; PNUTL3 antibody; SEP1 antibody; SEPT1 antibody; SEPT1_HUMAN antibody; Septin 1 antibody; Septin-1 antibody; Serologically defined breast cancer antigen NY BR 24 antibody; Serologically defined breast cancer antigen NY-BR-24 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human Septin 1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Gene References into Functions
  1. The SEPT1 may participate in cell-cell and/or cell-substrate interaction in DJM-1 and exert its function in a coordinated manner with other septins. PMID: 23087102
  2. Aurora-B binds and phosphorylates Septin1. PMID: 16179162
  3. An increase in Sept1 expression in all oral squamous-cell carcinoma-derived cell lines compared to human normal oral keratinocytes and oral premalignant lesions suggest that Sept1 expression could contribute to cancer progression, proliferation, or both. PMID: 17912427
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
Tissue Specificity
Expressed at high levels in lymphoid and hematopoietic tissues.
Database Links

HGNC: 2879

OMIM: 612897

KEGG: hsa:1731

STRING: 9606.ENSP00000460441

UniGene: Hs.632176

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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